Based on the daily meteorological observation data at 441 national meteorological stations in southwestern China in summer from 1961 to 2022, the basic climatic situation, characteristics of high temperature and drought disasters and their main impacts in southwestern China in summer 2022 are analyzed. The results show that the severity of this extreme high temperature and drought event is historically rare. Compared with the historical corresponding period, the average temperature and the extreme maximum temperature were the highest, the precipitation was the least, and the high-temperature days was the most in the summer of 2022 in southwestern China. In addition, the persistent high temperature was accompanied by a severe meteorological drought in eastern part of southwestern China. The 105 meteorological stations of the central Xizang, most areas of Sichuan, most areas of Chongqing, the north of Guizhou and local regions of central Yunnan happened extreme droughts. Under the impacts of the compound high temperature and drought, the output of some crops in the east of southwest China reduced, even extremely, the inflow of rivers appeared a rare phenomenon of ‘returning to dry in flood season’, and the power load hit a new record and the hydropower generation decreased sharply, resulting in a shortage of energy supply. Moreover, several forest fires broke out in eastern Sichuan Basin and western Chongqing. This article aims to understand this extreme high temperature and drought event from a scientific perspective, facilitate the development of meteorological disaster risk assessment, provide scientific and technological support for improving disaster prevention and mitigation and dealing with climate change.